Wegovy Dosing Chart and Weekly Schedule

An illustration depicting a five-step staircase with an ascending arrow above it, and a red circle and blue dashes floating in the space. This symbolizes a step-by-step dose escalation schedule, such as for Wegovy.

Wegovy Dosing Chart: Weekly Schedule & Dose Tips

Updated October 2025

Important safety note

  • This guide is for education only. It is not medical advice. Always follow your prescriber’s directions and the FDA label. If you have questions about your dose or side effects, talk to your doctor or pharmacist right away.
  • See the FDA label and official resources: Wegovy dosing scheduleFDA Prescribing Information (2025)

Wegovy (semaglutide) is a once‑weekly injection. Approved uses include:

  • Chronic weight management in adults and adolescents 12+ with obesity (or in adults who are overweight with weight‑related conditions)
  • Reducing the risk of major cardiovascular events in certain adults with established cardiovascular disease and obesity/overweight
  • Treating MASH (metabolic dysfunction‑associated steatohepatitis) with moderate‑to‑advanced fibrosis in adults

Sources: FDA label; MASH dosing schedule

Don’t use Wegovy with other semaglutide products or GLP‑1 medicines (see the official dosing page).


Wegovy Dosing Chart & Standard Escalation Schedule

A simple bar chart with five bars of increasing height, visually representing the dose escalation schedule for Wegovy. The bars are in shades of green, yellow, and red.

Wegovy doses typically increase every 4 weeks to help your body adjust and limit stomach side effects.

WeeksWeekly Dose
1–40.25 mg
5–80.5 mg
9–121 mg
13–161.7 mg
17+Maintenance: 2.4 mg weekly (or 1.7 mg if 2.4 mg isn’t tolerated)

Helpful notes

  • Adults and teens 12+ generally follow this same step‑up plan under medical supervision.
  • If side effects are difficult to tolerate when you increase your dose, your prescriber may extend that step before moving up.

Sources: Wegovy dosing schedule; FDA label; Healthline dosage overview; GoodRx dosage guide


Missed a Dose? Use the 48‑Hour / 2‑Week Rule

  • If your next scheduled dose is more than 48 hours away: take the missed dose as soon as you remember.
  • If your next scheduled dose is within 48 hours: skip the missed dose and take the next dose on your usual day.
  • If it’s been 2+ weeks since your last dose: take your next dose on your regular day, and ask your prescriber if you should restart at a lower step first.

Tip: You can change your weekly injection day if needed—as long as at least 2 days have passed since your last dose.

Sources: Wegovy dosing schedule; FDA label


How to Inject Wegovy (Quick Start)

A diagram showing the three recommended injection sites for Wegovy on a human silhouette: the abdomen, front of the thigh, and back of the upper arm.
  • Take it once weekly, on the same day each week.
  • Inject into the abdomen, thigh, or upper arm.
  • Use the single‑use, prefilled pen for your prescribed dose.
  • Store pens in the refrigerator (36–46 °F / 2–8 °C).
  • Pens may be kept at room temperature (46–86 °F / 8–30 °C) for up to 28 days.
  • Protect from light and do not freeze.
  • Dispose of used pens in a sharps container.

Sources: GoodRx; FDA label


Managing Common Side Effects

A close-up, top-down view of a small white bowl filled with creamy yogurt, topped with a mix of fresh raspberries, blueberries, and a single strawberry, along with a sprinkle of brown and green seeds. A silver spoon is positioned to the right of the bowl against a white background.

Nausea and a feeling of fullness are among the most common side effects reported as the dose increases. Try these strategies:

  • Eat smaller, slower meals and stop when you feel comfortably full.
  • Prioritize protein‑rich foods with cooked vegetables; avoid heavy, greasy meals.
  • Sip fluids through the day to prevent dehydration.
  • Add fiber gradually to limit bloating.
  • If symptoms are severe or persistent (e.g., ongoing vomiting or severe belly pain), call your clinician. They may pause a dose increase or hold your current step.
A hand holds a clear glass filled with water and several ice cubes. The background is a soft, muted tone, and natural light casts gentle shadows on the scene.

Choosing Your Maintenance Dose: 1.7 mg vs 2.4 mg

  • Many adults end up at 2.4 mg weekly, the maximum dose used for weight management and cardiovascular risk reduction in appropriate patients.
  • Others stay at 1.7 mg for tolerability. The “best” dose is the one you can stick with—decide this with your prescriber.

Sources: FDA label; Wegovy dosing schedule


Track What Matters: Body Fat vs Muscle With BodySpec DEXA

An illustration showing two human silhouettes. The silhouette on the left contains yellow, blob-like shapes representing high body fat. The silhouette on the right shows red striated patterns representing high muscle mass, contrasting body composition.

If you’re using Wegovy, the scale alone can be confusing. You want to lose fat, not hard‑earned muscle—and that’s exactly what a DEXA scan shows. BodySpec’s medical‑grade DEXA quantifies:

  • Total body fat percentage and regional fat
  • Visceral fat (the deeper belly fat linked to health risk)
  • Lean (muscle) mass by limb and total body
  • Bone density

Why it helps during GLP‑1 therapy

A close-up shot of a muscular hand gripping the knurled handle of a heavy, dark-colored dumbbell, highlighting the texture of both the hand and the weight.
  • GLP‑1s can curb appetite quickly. Pairing Wegovy with strength training and adequate protein helps protect muscle. DEXA lets you confirm you’re losing mostly fat, and adjust early if needed.

A simple tracking plan

  • Get a baseline scan before or at the start of treatment.
  • Re‑scan at 8–12 weeks (around the time you reach 1.0–1.7 mg) to check fat vs muscle changes.
  • Re‑scan again once you’re on a maintenance dose to confirm your strategy is effective.

Track your progress with DEXA:


Quick‑Start Checklist

An illustration of a checklist on a clipboard. Three circular checkboxes are marked with green checkmarks, and lines to their right represent text.
  • Pick a weekly injection day/time and set 2 reminders (phone + calendar).
  • Follow the week‑by‑week chart—don’t increase early.
  • Keep meals small and protein‑forward; hydrate.
  • Rotate injection sites; store pens correctly.
  • If you miss a dose, use the 48‑hour/2‑week rules above.
  • Call your clinician for severe or persistent symptoms.

Reminder: This article is informational and not a substitute for medical advice. Always follow your healthcare professional’s guidance and the FDA label.

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